14549 Minetta St., Houston TX 77035


Research/Sr. Scientist – Enzymology Process Development

About Solugen

At Solugen, we believe planet-scale change starts with the chemistry we use every day. So we’ve built the world’s first carbon negative molecule factory. Fusing biology with chemistry and technology to make the materials we need to sustain life on Earth.

Solugen, Inc. is a revolutionary product and technology company seeking to use biology to transform the chemicals industry. Solugen was founded in 2016 and is a post-Series C venture-backed biotechnology company supported by renowned venture capital firms including Founders Fund, FiftyYears, Refactor, Y Combinator, Temasek, GIC, and Baillie-Gifford. Located in Houston, Texas, Solugen currently has 100+ full time employees.


Solugen’s mission is to decarbonize chemicals manufacturing. As a first step, Solugen is building a 10,000 tpy first commercial plant with the potential to offset up to 37,000 tpy of carbon dioxide equivalents. This role will directly support Solugen’s mission by continuously improving Solugen’s core catalytic platform. As the activity, selectivity, stability, and manufacturing cost of Solugen’s core catalytic platform continuously improves, the quality of Solugen’s products and our cost to manufacture improve.

Key Outcomes


  1. Design and execute enzyme process development experiments.
  2. Maintain a safe and orderly laboratory in compliance with all safety policies and practices.
  3. Write standard operating procedures related to enzyme technologies.
  4. Initiate and monitor benchtop experiments under the direction of the R&D team.
  5. Engage in new product design, development, and testing.
  6. Collaborate with the Process Development team to steer experiments and report findings.

Key Competencies

Job Specific

  • Attention to detail and organization.
  • Ability to exercise common molecular biology techniques including microbial cell culture, sterile field technique, isolation of nucleic acids, polymerase chain reaction, cloning, restriction digests, nucleic acid and protein gel electrophoresis, centrifugation, autoclaving, and pipetting.
  • Willingness to self-learn a broad range of new technical skills.
  • Ability to plan and execute design of experiments exercises.
  • Ability to run chemical reactors including bioreactors and high-pressure vessels.
  • Ability to run fermentation experiments for protein production, enzymes preferred, in deep well plates, shake flasks, and fermentors.
  • Ability to generate reports and visualize data in an organized, timely, quantitative, and thorough manner.
  • Good communication, negotiation, leadership, and project management skills with the desire to further develop these skills as the company grows.
  • Comfortable following safety protocols and wearing personal protective equipment—including laboratory coats, eye protection, and close toed shoes --in work zones.
  • Good familiarity with Office products as well as a general level of comfort with online communication and work management platforms such as Dropbox, Google Doc, and Slack.
  • Analytical approach to problem solving, with a focus on managing a team environment with attention to results and a sense of urgency.

Company Specific

  • Be nimble, embrace the speed and ambiguity of startup culture.
  • A passion for green chemistry and fighting climate change.
  • Ability to self-manage and set your own priorities and schedule.
  • Be comfortable working in multiple roles.
  • Emphasize safety above all else.
  • Respect for others.
  • Creative problem solving.
  • Willingness to learn and research new engineering/science concepts.


A BS, MS, PhD, or work experience in molecular biology, biochemistry, bioengineering, chemical engineering or related field with heavy emphasis on process development for chemical reactions.

This is a full-time position located in Houston, Texas.

Solugen is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, gender, sexual orientation, national origin, disability status, protected veteran status or any other legally protected status.