Solugen

14549 Minetta St., Houston TX 77035

Position

Senior Scientist – Strain engineering

About Solugen

With innovation and the commitment to lowering carbon footprint, Solugen Inc. is commercializing a chemo-enzymatic process to manufacture value-added chemicals from biobased feedstocks for a variety of uses and applications. Solugen was founded in 2016 and is a venture-backed startup company located in Houston, TX. Solugen is scaling up its manufacturing process on 5 acres of manufacturing space with a 65,000 square foot facility containing 10,000 square feet of office and lab space. Solugen currently has 100+ full time employees.

Mission

Solugen’s mission is to decarbonize chemicals manufacturing. As a first step, Solugen is building its first 10,000 tons per year commercial plant with potential to offset 37,000 tons per year of carbon dioxide equivalents. This role will directly support Solugen’s mission by continuously improving our ability to scale enzyme production to support our core platform. The individual will report to the Head of Strain Engineering and assist with experiments and analysis to support the Solugen’s future R&D, production, and revenue goals. This role will be involved with genetically engineering Solugen’s production hosts to maximize their performance. As the production strains continuously improve, the quality of Solugen’s products and our cost to manufacture improve. This is a hands-on role where the individual’s initiative, laboratory prowess, and energy will make a substantial impact on the company.

Key Outcomes

  • Develop and execute strategies to increase heterologous protein production titers in bacteria, yeast, and filamentous fungi.
  • Independently perform experiments to record and analyze key performance indicators of production strains.
  • Visualize data analysis and deliver results on a timely manner.

Key Competencies

Job Specific:

  • PhD in Biotechnology, Biology, Microbiology, Biochemistry, or related field with a focus on genetic engineering of eukaryotic microorganisms and heterologous protein expression
  • 2-3 years of academic or industrial experience in genetic engineering of eukaryotic microorganisms and heterologous protein expression with a proven track record of achievements
  • Able to translate deep knowledge of heterologous protein production hosts genetics into titer improvements in the lab through hands-on skills
  • Experienced in genome editing of Trichoderma reesei, Aspergillus niger, and Pichia pastoris
  • Experienced with genome sequencing and annotation of eukaryotic organisms using state of the art techniques (Illumina, Nanopore, etc.)
  • Familiar with scaling-up and -down of bioprocesses: Automated high-throughput screening using robotics and able to translate to bioreactor scale
  • Molecular techniques in protein and RNA isolation, purification, and analysis are second nature to you
  • Versed in relevant analytical software (Empower, Geneious Prime, JMP) and able to streamline data analysis and visualization from benchtop equipment through Python and R.
  • Must be able to prioritize and self-organize with a mindset to succeed
  • Good communicator with excellent verbal and writing skills

Company Specific:

  • Curiosity and willingness to learn and ask a lot of questions
  • Being nimble, embracing the speed of startup culture
  • Passionate for green chemistry and fighting climate change
  • Emphasis on safety
  • Respect for others

Qualifications:

  • PhD in Biotechnology, Biology, Microbiology, Biochemistry, or related field with a focus on genetic engineering of eukaryotic microorganisms and heterologous protein expression
  • 2-3 years of academic or industrial experience in genetic engineering of eukaryotic microorganisms and heterologous protein expression with a proven track record of achievements



Solugen is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, gender, sexual orientation, national origin, disability status, protected veteran status or any other legally protected status.